Lysergic acid diethylamide
| LSD, LSD-25 | |
|---|---|
| Salts [] | |
|---|---|
| Lysergic acid diethylamide maleate | |
| Lysergic acid diethylamide tartrate | |
| Lysergic acid diethylamide hydrobromide | |
| Molecular structure via molpic based on CDK |
| Physical properties [] | |
|---|---|
| Molecular mass | 323.4 g/mol [1] |
| Appearance | Pointed prisms from benzene [1] |
| Odor | Odorless [1] |
| Taste | Tasteless [1] |
| Melting point | 176 to 185 °F (NTP, 1992) [1] |
| Decomposition | When heated to decomposition it emits toxic fumes of /nitrogen oxides/. [1] |
| Solubility | Water soluble [1] |
| Predicted LogP | 3 [1] |
| Structural Identifiers [] | |
|---|---|
| Molecular formula | C20H25N3O [1] |
| IUPAC name | (6aR,9R)-N,N-diethyl-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide [1] |
| SMILES | CCN(CC)C(=O)[C@H]1CN([C@@H]2CC3=CNC4=CC=CC(=C34)C2=C1)C [1] |
| InChI | InChI=1S/C20H25N3O/c1-4-23(5-2)20(24)14-9-16-15-7-6-8-17-19(15)13(11-21-17)10-18(16)22(3)12-14/h6-9,11,14,18,21H,4-5,10,12H2,1-3H3/t14-,18-/m1/s1 [1] |
| InChIKey | VAYOSLLFUXYJDT-RDTXWAMCSA-N [1] |
| Pharmacokinetics[] | |
|---|---|
| Elimination half-life | 3.6 hours |
| Duration of action | Oral administration|Oral: 7 – 12 (range 4 – 22) hoursIntramuscular injection, Intravenous injection, Intrathecal injection: 8 – 10 hours |
| Dosing[] |
|---|
| Sublingual [] | |
|---|---|
| Light | ≤ 0.2 mg(2x - 25%) |
| Common | 0.2 - 0.3 mg(4x - 50%) |
| Strong | 0.3 mg |
| Heavy | 0.3 - 0.5 mg(1x - 12.5%) |
| Extreme | 0.5 mg +(1x - 12.5%) |
| Oral [] | |
|---|---|
| Light | ≤ 0.2 mg(6x - 26.1%) |
| Common | 0.2 - 0.3 mg(7x - 30.4%) |
| Strong | 0.3 - 0.6 mg(4x - 17.4%) |
| Heavy | 0.6 - 0.8 mg(4x - 17.4%) |
| Extreme | 0.8 mg +(2x - 8.7%) |
Statistically derived dosages via DBI-IGS We do not take any responsibility for medical complications or loss of life sustained by following these dosages blindly. |
Lysergic acid diethylamide (also known as Lysergide, Lysergic acid diethylamide, Lsd, N,N-Diethyllysergamide, Lysergsaeurediaethylamid, N,N-Diethyl-D-lysergamide, Lysergaure diethylamid, LSD-25, LSD 25 or Lisergide) is a psychedelic substance of the lysergamide class.
Chemistry
Salts []
Lysergic acid diethylamide is typically found in the form of its maleate, tartrate and hydrobromide salts.
Stereochemistry []
Lysergic acid diethylamide is a absolute mixture.
Subjective effects []
| alina / Lysergic acid diethylamide [] | |
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| bonzi / Lysergic acid diethylamide [] | |
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| emily / Lysergic acid diethylamide [] | |
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| x86pup / Lysergic acid diethylamide [] | |
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| magnus / Lysergic acid diethylamide [] | |
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| Mere / Lysergic acid diethylamide [] | |
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| 0xea / Lysergic acid diethylamide [] | |
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Experience reports []
There are currently 25+ experience reports involving lysergic acid diethylamide on Erowid:
- "Military LSD Testing" by GKS
- "5 Hits?" by Ssomeone Else
- "All But Nothing" by Ciccione Youth
- "I Wonder What Else I Can't Feel in Life" by woe
- "The Effects Never Came" by T
- "Unaffected on Antidepressants" by Adina
- "No Trip with Subutex" by Craig M
- "Two Months Wasn't Enough" by Dr. Rhodes
- "LSD Microdosing RCT" by Gwern.net
- "AcidAlbizia. Where's My Chinese Happiness" by bradkehlerits me
- "LSD Less Effective For Me" by Sktbx
- "My experiences with LSD" by Del Neshom
- "Out of Body LSD" by Misphunkshinz
- "A Sudden Respect for the Complexity of Things" by Anonymous
- "Mind Painting" by Murple
- "An LSD Let Down" by Dark Star
- "Beyond What is Real" by Crazy S
- "A Psychedelic Way of Life" by Smiling Sound
- "Visual Administration" by TheOtherSide
- "LSD & Dreaming" by Satan Himself
- "External to My Own Self" by Penguin Butler
- "It Took Forever" by Dr. Copious
- "I Can Understand!" by The Correspondent
- "HPPD and Other Drugs" by Confused
- "Microdoses: Consistent Desired Results" by Samanthe
Legal status []
- Australia: Lysergic acid diethylamide is a Schedule 9 substance.
- Brazil: Lysergic acid diethylamide is a F2 substance.
- Canada: Lysergic acid diethylamide is a Schedule III substance.
- New Zealand: Lysergic acid diethylamide is a Class A substance.
- United Kingdom: Lysergic acid diethylamide is a Class A substance.
- United Nations: Lysergic acid diethylamide is a Schedule I drug under the "Convention on Psychotropic Substances 1971".
- United States: Lysergic acid diethylamide is a Schedule I under the "Controlled Substances Act (CSA)".
- Germany: Lysergic acid diethylamide is a Anlage I substance.
See also []
External links []
- Lysergic acid diethylamide (Wikipedia)
- Lysergic acid diethylamide (Wikidata)
- Lysergic acid diethylamide (DrugBank)
- Lysergic acid diethylamide (PubChem)
- Lysergic acid diethylamide (Common Chemistry)
- Lysergic acid diethylamide (KEGG)
- Lysergic acid diethylamide (UNII)
- Lysergic acid diethylamide (EPA DSSTox)
References []
National Center for Biotechnology Information. PubChem Compound Summary for CID 5761, Lysergide. Accessed May 16, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/5761
U.S. Food and Drug Administration; National Center for Advancing Translational Sciences. Lysergic acid diethylamide. UNII: 8NA5SWF92O. Global Substance Registration System. Accessed May 16, 2026. https://gsrs.ncats.nih.gov/ginas/app/beta/substances/8NA5SWF92O